COMPARING TREATMENT ALGORITHMS
IN ADULT BRACHIAL PLEXUS INJURY


A prospective observational study

comparing treatment strategies in adult brachial plexus injury


Goal is to find the most effective and efficient treatment strategy for better outcomes after severe brachial plexus injury

Research Questions

Optimal strategy?

What is the best surgical strategy for reconstruction of arm and hand function in adult traumatic brachial plexus injury?

Optimal setting?

What is the best treatment strategy and setting for treatement of rare ATBPI in terms of functional outcome and QoL?

Background

Current level of evidence is low


There is a wide variety in treatment algorithms for arm function reconstruction after Adult Brachial Plexus Injury.


There is a need for international and multidisciplinary collaboration in which past dogmas will be left behind and innovative approaches undertaken.



Outcome?


There are no studies performed on functional outcome and Quality of Life (QoL) in ABPI;

Primary/Secondary


Reconstruction of arm and hand function after ABPI is performed in a staged treatment fashion, making it suitable for CER


Combining nerve surgery and secondary tendon transfers at various moments we can use single patient trial


Methods

Prospective observational study

exploiting treatment preferences to create and compare similar treatment groups (CER);


Build a network of trauma centers specialized in treatment of ABPI


Outcome measures:

Minimal outcome set: COS-TBPI (Miller JHSE 2023): BraT (Hill 2017), BPI, Plasticity grade (Socolovsky JNS 2023), Donor site morbidity.

Minimal follow up 3 years

Timetable:

July25: building co-ops 

October 25 Research protocol

December 25: Survey/Provider Profiling results

May 26: start inclusion CER